HII-CHI-mistry calculates the oxygen abundance for gaseous nebulae ionized by massive stars using optical collisionally excited emission lines. This code takes the extinction-corrected emission line fluxes and, based on a Χ2 minimization on a photoionization models grid, determines chemical-abundances (O/H, N/O) and ionization parameters. An ultraviolet version of this Python code, HII-CHI-mistry-UV (ascl:1807.008), is also available.