nuance uses linear models and Gaussian processes to simultaneously search for planetary transits while modeling correlated noises (e.g., stellar variability). The code computes the likelihood of a transit being present in some correlated noise without disentangling the two; it searches the transit signal while simultaneously modeling correlated noise, assuming that the light curve can be modeled as a Gaussian process. nuance detects single or periodic transits and can find transits in light curves from multiple instruments, whether space-based or ground-based; it can also run in parallel on CPUs or GPUs.