21cmFAST is a powerful semi-numeric modeling tool designed to efficiently simulate the cosmological 21-cm signal. The code generates 3D realizations of evolved density, ionization, peculiar velocity, and spin temperature fields, which it then combines to compute the 21-cm brightness temperature. Although the physical processes are treated with approximate methods, the results were compared to a state-of-the-art large-scale hydrodynamic simulation, and the findings indicate good agreement on scales pertinent to the upcoming observations (>~ 1 Mpc). The power spectra from 21cmFAST agree with those generated from the numerical simulation to within 10s of percent, down to the Nyquist frequency. Results were shown from a 1 Gpc simulation which tracks the cosmic 21-cm signal down from z=250, highlighting the various interesting epochs. Depending on the desired resolution, 21cmFAST can compute a redshift realization on a single processor in just a few minutes. The code is fast, efficient, customizable and publicly available, making it a useful tool for 21-cm parameter studies.