The parallel Python framework MLZ (Machine Learning and photo-Z) computes fast and robust photometric redshift PDFs using Machine Learning algorithms. It uses a supervised technique with prediction trees and random forest through TPZ that can be used for a regression or a classification problem, or a unsupervised methods with self organizing maps and random atlas called SOMz. These machine learning implementations can be efficiently combined into a more powerful one resulting in robust and accurate probability distributions for photometric redshifts.