Skyoffset makes wide-field mosaics of FITS images. Principal features of Skyoffset are the ability to produce a mosaic with a continuous background level by solving for sky offsets that minimize the intensity differences between overlapping images, and its handling of hierarchies, making it ideal for optimizing backgrounds in large mosaics made with array cameras (such as CFHT’s MegaCam and WIRCam). Skyoffset uses MongoDB in conjunction with Mo’Astro (ascl:2104.012) to store metadata about each mosaic and SWarp (ascl:1010.068) to handle image combination and propagate uncertainty maps. Skyoffset can be integrated into Python pipelines and offers a convenient API and metadata storage in MongoDB. It was developed originally for the Andromeda Optical and Infrared Disk Survey (ANDROIDS).