Chem-I-Calc evaluates the chemical information content of resolved star spectroscopy. It takes advantage of the Fisher information matrix and the Cramér-Rao inequality to quickly calculate the Cramér-Rao lower bounds (CRLBs), which give the best theoretically achievable precision from a set of observations.
https://ui.adsabs.harvard.edu/abs/2020ApJS..249...24S and https://ui.adsabs.harvard.edu/abs/2020zndo...3924672S