stimela provides a system-agnostic scripting framework for simulating, processing, and imaging radio interferometric data. The framework executes radio interferometry related tasks such as imaging, calibration, and data synthesis in Docker containers using Python modules. stimela offers a simple interface to packages that perform these tasks rather than doing any data processing, synthesis or analysis itself. stimela only requires Docker and Python. Moreover, because of Docker, a stimela script runs the same way (in the same iso­lated environment) regardless of the host machine’s settings, thus providing a user-friendly and modular scripting environment that gives general users easy access to novel radio interferometry calibration, imaging, and synthesis packages.