FishLSS computes the Fisher information matrix for a set of observables and model parameters. It can model the redshift-space power spectrum of any biased tracer of the CDM+baryon field and the post-reconstruction galaxy power spectrum. The code also models the projected cross-correlation of galaxies with the CMB lensing convergence, the projected galaxy power spectrum, and the CMB lensing convergence power spectrum. FishLSS requires pyFFTW (ascl:2109.009), velocileptors (ascl:2308.014), and CLASS (ascl:1106.020).