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TESSreduce builds on lightkurve (ascl:1812.013) to reduce TESS data while preserving transient signals. It takes a TPF as input (supplied or constructed with TESScut (https://mast.stsci.edu/tesscut/). The background subtraction accounts for the smooth background and detector straps. In addition to background subtraction, TESSreduce also aligns images, performs difference imaging, detects transient events, and by using PS1 data, can calibrate TESS counts to physical flux or AB magnitudes.