D2O acts as a layer of abstraction between algorithm code and data-distribution logic to manage cluster-distributed multi-dimensional numerical arrays; this provides usability without losing numerical performance and scalability. D2O's global interface makes the cluster node's local data directly accessible for use in customized high-performance modules. D2O is written in Python; the code is portable and easy to use and modify. Expensive operations are carried out by dedicated external libraries like numpy and mpi4py and performance scales well when moving to an MPI cluster. In combination with NIFTy, D2O enables supercomputer based astronomical imaging via RESOLVE (ascl:1505.028) and D3PO (ascl:1504.018).

IMAGINE (Interstellar MAGnetic field INference Engine) performs inference on generic parametric models of the Galaxy. The modular open source framework uses highly optimized tools and technology such as the MultiNest sampler (ascl:1109.006) and the information field theory framework NIFTy (ascl:1302.013) to create an instance of the Milky Way based on a set of parameters for physical observables, using Bayesian statistics to judge the mismatch between measured data and model prediction. The flexibility of the IMAGINE framework allows for simple refitting for newly available data sets and makes state-of-the-art Bayesian methods easily accessible particularly for random components of the Galactic magnetic field.